Alesse

Alesse is used to prevent ovulation and pregnancy.

Product dosage: 0.18mg
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Synonyms Aviane-28 Enpresse Microgynon Nordette Ovral-l Seasonale Trinordiol Triphasil Triquilar Trivora

Alesse is a combination oral contraceptive pill trusted by healthcare providers for its dual-action formulation. It effectively prevents pregnancy through a carefully balanced low-dose hormone regimen while also offering the benefit of improving moderate acne in women who choose this method for birth control. Its monophasic design ensures consistent hormone levels throughout the cycle, supporting predictable efficacy and tolerability.

Features

• Contains a combination of ethinyl estradiol (20 mcg) and levonorgestrel (0.1 mg)
• Monophasic formulation: each active pill delivers the same hormone dose
• 28-day cycle pack: 21 active tablets and 7 inert reminder tablets
• Low-dose estrogen profile aimed at minimizing common side effects
• FDA-approved for both contraception and the treatment of moderate acne

Benefits

• Highly effective at preventing pregnancy when taken correctly, with a Pearl Index of approximately 0.3–1.2 per 100 woman-years
• Can lead to clearer skin by reducing sebum production and androgen-related acne
• Often results in lighter, more regular, and less painful menstrual periods
• May reduce the risk of ovarian cysts, ectopic pregnancy, and iron-deficiency anemia
• Provides non-contraceptive benefits including potential improvement in premenstrual symptoms
• Offers convenience and discretion as a daily oral regimen

Common use

Alesse is primarily prescribed for the prevention of pregnancy in women of reproductive age. It is also commonly used off-label or as an approved secondary benefit for the management of moderate acne vulgaris in females seeking oral contraception. Some clinicians may recommend it for cycle regulation in women with irregular menses, provided there are no contraindications.

Dosage and direction

Take one tablet by mouth at the same time each day, for 28 consecutive days: 21 active tablets followed by 7 inert tablets. Begin the first pack on the first Sunday after menstruation starts or on the first day of menstruation (depending on provider guidance). If switching from another hormonal contraceptive, follow specific instructions from a healthcare professional. Use a backup contraceptive method, such as condoms, for the first 7 days of the first cycle.

Precautions

• Not protective against sexually transmitted infections (STIs)
• Cigarette smoking increases the risk of serious cardiovascular side effects, especially in women over 35 years of age
• May influence lipid metabolism, blood pressure, and glucose tolerance; periodic monitoring is advised
• Reduced efficacy may occur with gastrointestinal illnesses, such as vomiting or diarrhea
• Alert healthcare providers prior to surgical procedures or prolonged immobilization due to increased thrombosis risk

Contraindications

• History of or current thrombotic disorders (e.g., DVT, PE, stroke, MI)
• Estrogen-dependent neoplasia, such as breast or endometrial cancer
• Undiagnosed abnormal genital bleeding
• Liver tumors, acute or chronic severe liver disease
• Known or suspected pregnancy
• Hypersensitivity to any component of Alesse

Possible side effects

Common side effects may include:

• Nausea, vomiting, or abdominal cramps
• Headache or migraine
• Breast tenderness or enlargement
• Irregular bleeding or spotting, especially during the first few cycles
• Changes in weight or mood
• Diminished libido

Serious (though rare) side effects require immediate medical attention:

• Sudden vision changes or loss
• Severe chest pain, shortness of breath, or hemoptysis
• Jaundice, severe abdominal pain, or liver enlargement
• Sudden severe headache, dizziness, or numbness

Drug interaction

Alesse may interact with:

• Antibiotics (e.g., rifampin, griseofulvin)
• Anticonvulsants (e.g., carbamazepine, phenytoin)
• Antifungals (e.g., ketoconazole)
• HIV medications (e.g., ritonavir)
• St. John’s Wort and other herbal supplements
• Other drugs that induce hepatic enzymes, potentially reducing contraceptive efficacy

Missed dose

If one active pill is missed (24–48 hours late): take it as soon as remembered, and continue the pack as scheduled.
If two active pills are missed in a row in Weeks 1 or 2: take two pills on the day remembered, two the next day, then resume daily dosing; use backup contraception for 7 days.
If three or more active pills are missed: discard the pack, begin a new pack on the following Sunday, and use backup contraception until 7 consecutive active pills have been taken.
If pills are missed during the third week or inert tablet week: consult package insert or a healthcare provider for specific instructions.

Overdose

Serious ill effects have not been reported following large ingestions. Overdose may cause nausea, vomiting, or withdrawal bleeding. There is no specific antidote; symptomatic and supportive care is recommended.

Storage

Store at room temperature (20–25°C or 68–77°F). Keep in the original blister pack, away from moisture, light, and children. Do not use beyond the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider before starting, changing, or stopping any medication. Individual patient needs and medical history must be evaluated to determine the appropriateness of Alesse.

Reviews

Many users report high satisfaction with Alesse for its effective contraception and positive effects on acne and menstrual regularity. Some note initial side effects such as mild nausea or mood changes, which often subside after the first few cycles. Healthcare professionals frequently recommend it as a well-tolerated, low-dose option for new oral contraceptive users.