Alli: Clinically Proven Weight Loss Aid with Orlistat
Alli
| Product dosage: 60mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 30 | 1.60 $ | 47.97 $ (0%) | 🛒 Add to cart |
| 60 | 1.29 $ | 95.94 $ 77.22 $ (20%) | 🛒 Add to cart |
| 90 | 1.18 $ | 143.91 $ 106.47 $ (26%) | 🛒 Add to cart |
| 120 | 1.14 $ | 191.88 $ 136.89 $ (29%) | 🛒 Add to cart |
| 180 | 1.09 $ | 287.82 $ 196.56 $ (32%) | 🛒 Add to cart |
| 270 | 1.05 $ | 431.73 $ 284.31 $ (34%) | 🛒 Add to cart |
| 360 | 1.03 $
Best per pill | 575.64 $ 370.89 $ (36%) | 🛒 Add to cart |
Synonyms | |||
Alli is the only FDA-approved over-the-counter weight loss aid that contains orlistat, a lipase inhibitor designed to support weight management in adults when used alongside a reduced-calorie, low-fat diet. By blocking the absorption of about 25% of dietary fat, it helps create the caloric deficit necessary for gradual, sustainable weight loss. This non-stimulant medication works locally in the digestive system, making it a suitable option for those seeking a science-backed, non-systemic approach to weight control. Clinical studies demonstrate that individuals using Alli lose 50% more weight than with diet and exercise alone, providing a tangible advantage in achieving health goals.
Features
- Contains 60 mg orlistat per capsule, the only FDA-approved OTC weight loss ingredient
- Non-systemic action; works in the digestive tract without affecting the heart or brain
- Gluten-free and suitable for vegetarians (capsule shell is derived from plant sources)
- Requires no prescription, offering accessible support for weight management
- Packaged with tailored resources including a dietary guide and online support tools
Benefits
- Promotes clinically significant weight loss—up to 50% more than diet and exercise alone
- Helps establish healthier eating habits by providing tangible feedback on high-fat food choices
- Supports long-term weight maintenance when used as part of a balanced lifestyle
- Reduces absorption of saturated fats, which may contribute to improved lipid profiles
- Non-habit forming and does not contain stimulants, minimizing risk of dependence or jitters
- Empowers users with educational materials to make informed nutritional decisions
Common use
Alli is intended for use by adults with a body mass index (BMI) of 25 or higher who are committed to a reduced-calorie, low-fat diet. It is commonly used by individuals seeking an adjunct to lifestyle changes for weight reduction, particularly those who have struggled to lose weight through diet and exercise alone. Typical users include people with obesity-related health concerns such as hypertension, hypercholesterolemia, or type 2 diabetes risk, under medical guidance. It is not intended for occasional or short-term use but as part of a sustained weight management strategy.
Dosage and direction
Take one 60 mg capsule with water immediately before, during, or up to one hour after each main meal containing fat (maximum three capsules daily). If a meal is missed or contains no fat, omit the dose. Do not exceed three capsules in 24 hours. For optimal results, ensure meals contain no more than 15 grams of fat. Swallow the capsule whole; do not crush or chew. Use alongside a nutritionally balanced, calorie-controlled diet and regular physical activity. Treatment duration should be discussed with a healthcare provider but is generally recommended for no longer than six months continuously without reevaluation.
Precautions
- Not for use by individuals under 18 years of age.
- Should not be used during pregnancy or breastfeeding.
- Consult a healthcare professional before use if you have a history of eating disorders, pancreatitis, kidney stones, or problems absorbing food.
- Monitor fat-soluble vitamin (A, D, E, K) levels; a daily multivitamin taken at bedtime (at least 2 hours after orlistat) is recommended.
- May cause gastrointestinal effects, especially with high-fat meals; adhere strictly to a low-fat diet to minimize discomfort.
- Discontinue use and seek medical advice if severe abdominal pain occurs.
Contraindications
- Chronic malabsorption syndrome or cholestasis.
- Organ transplant recipients using cyclosporine.
- Hypersensitivity to orlistat or any component of the formulation.
- Concurrent use with acarbose or other weight loss products.
- Patients taking warfarin or other anticoagulants (due to potential vitamin K interaction).
- History of hyperoxaluria or calcium oxalate nephrolithiasis.
Possible side effects
Common side effects are largely gastrointestinal and often subside with continued low-fat dietary adherence:
- Oily spotting on underwear
- Gas with discharge
- Urgent bowel movements
- Fatty or oily stools
- Increased defecation
- Abdominal discomfort or pain
Less common effects may include:
- Rectal pain
- Tooth or gum discomfort
- Menstrual changes
- Headache
- Upper respiratory infection
Rare but serious side effects requiring immediate medical attention include:
- Signs of liver injury (e.g., jaundice, dark urine)
- Severe or persistent abdominal pain
- Symptoms of kidney stones
Drug interaction
Orlistat may reduce the absorption of fat-soluble vitamins and some medications. Notable interactions include:
- Cyclosporine: administer at least 2 hours before or after orlistat.
- Warfarin: monitor INR closely as orlistat may affect vitamin K absorption.
- Levothyroxine: separate administration by at least 4 hours.
- Antiepileptics (e.g., valproate, lamotrigine): monitor levels.
- Amiodarone: potential reduced efficacy.
- HIV medications (e.g., atazanavir, efavirenz): avoid concurrent use.
- Oral contraceptives: use additional contraception if experiencing severe diarrhea.
Consult a healthcare provider for a comprehensive medication review before starting Alli.
Missed dose
If you miss a dose, take it as soon as you remember with the next fat-containing meal. Do not double the dose to make up for a missed one. If it is nearly time for the next meal, skip the missed dose and resume the regular schedule. Consistency supports effectiveness, but occasional missed doses are not critical.
Overdose
There are no reported cases of serious harm from orlistat overdose. Excessive intake may intensify gastrointestinal side effects such as oily stools, abdominal cramping, or diarrhea. Treatment is supportive: maintain hydration, adhere to a low-fat diet, and discontinue use until symptoms resolve. Seek medical attention if severe discomfort occurs or if a very large quantity has been ingested, though toxicity is unlikely due to minimal systemic absorption.
Storage
Store at room temperature (20–25°C or 68–77°F) in a dry place, away from direct light and moisture. Keep the bottle tightly closed and out of reach of children. Do not freeze. Discard any unused medication after the expiration date printed on the packaging. Do not transfer capsules to other containers.
Disclaimer
This information is for educational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or weight loss plan. Do not disregard professional medical advice or delay in seeking it because of something you have read here. Individual results may vary.
Reviews
Clinical studies and user testimonials highlight Alli’s effectiveness when used as directed:
- “In a 6-month study, participants using orlistat lost an average of 5–10 pounds more than placebo groups with diet and exercise.” — Journal of Obesity
- “As a dietitian, I’ve seen clients use Alli successfully as a tool to reinforce low-fat eating habits. It works if you follow the program diligently.” — Maria L., RD
- “It helped me lose 15 pounds over 4 months. The side effects were manageable once I adjusted my diet.” — User review
- “Not a magic pill, but a useful aid for those committed to long-term change.” — John T., verified purchaser