Avodart: Clinically Proven BPH Symptom Relief
Avodart
| Product dosage: 0.5mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 20 | 2.34 $ | 46.80 $ (0%) | 🛒 Add to cart |
| 30 | 2.22 $ | 70.20 $ 66.69 $ (5%) | 🛒 Add to cart |
| 60 | 2.11 $ | 140.40 $ 126.36 $ (10%) | 🛒 Add to cart |
| 90 | 2.07 $ | 210.60 $ 186.03 $ (12%) | 🛒 Add to cart |
| 120 | 2.05 $ | 280.80 $ 245.70 $ (12%) | 🛒 Add to cart |
| 180 | 2.03 $ | 421.20 $ 365.04 $ (13%) | 🛒 Add to cart |
| 270 | 2.01 $ | 631.80 $ 542.88 $ (14%) | 🛒 Add to cart |
| 360 | 1.81 $
Best per pill | 842.40 $ 650.52 $ (23%) | 🛒 Add to cart |
Avodart (dutasteride) is a prescription medication specifically formulated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate. As a potent 5-alpha-reductase inhibitor, it works by reducing the production of dihydrotestosterone (DHT), a hormone that contributes to prostate growth. This reduction leads to a decrease in prostate size, improving urinary flow and alleviating associated symptoms over time. Clinical studies support its efficacy in managing BPH, making it a trusted option under physician guidance for long-term urinary health.
Features
- Active ingredient: Dutasteride 0.5 mg
- Mechanism: Dual inhibitor of both type 1 and type 2 isoforms of 5-alpha-reductase
- Form: Oral soft gelatin capsules
- Prescription-only medication
- Typically packaged in blister packs or bottles for patient convenience
- Manufactured under strict pharmaceutical quality controls
Benefits
- Reduces prostate size, leading to improved urinary flow and decreased symptoms of BPH
- Decreases the risk of acute urinary retention and the need for BPH-related surgery
- Provides long-term management of benign prostatic hyperplasia with once-daily dosing
- Supported by extensive clinical data demonstrating efficacy and safety in appropriate patients
- May contribute to enhanced quality of life through relief of obstructive and irritative urinary symptoms
Common use
Avodart is primarily indicated for the management of symptomatic benign prostatic hyperplasia in men with an enlarged prostate. It is used to improve urinary flow, reduce the incidence of acute urinary retention, and decrease the need for surgical interventions such as transurethral resection of the prostate (TURP). It is not approved for use in women or children, and it is not indicated for prostate cancer prevention, although it may be studied in that context under specific clinical protocols.
Dosage and direction
The recommended dosage of Avodart is one 0.5 mg capsule taken orally once daily, with or without food. It should be swallowed whole and not crushed or chewed, as this can alter absorption. Treatment response may take up to 6 months to manifest fully, and continued use is necessary to maintain therapeutic benefits. Dosage adjustments are not typically required for elderly patients or those with renal impairment, but caution is advised in hepatic impairment. Always follow the prescribing physician’s instructions.
Precautions
- Avodart is contraindicated in women, particularly those who are or may become pregnant, due to risk of fetal harm.
- Patients should be informed that Avodart may increase the risk of high-grade prostate cancer; regular monitoring is advised.
- Blood donation is prohibited during and for 6 months after treatment to prevent transmission to pregnant recipients.
- Caution is recommended in patients with liver dysfunction, as dutasteride is metabolized hepatically.
- Patients may experience changes in sexual function; counseling on potential effects is important before initiation.
Contraindications
- Hypersensitivity to dutasteride, other 5-alpha-reductase inhibitors, or any component of the formulation.
- Use in women, especially those who are pregnant or of childbearing potential.
- Pediatric use is not recommended.
Possible side effect
Common side effects may include:
- Decreased libido
- Erectile dysfunction
- Ejaculation disorders
- Breast enlargement or tenderness
Less frequently, patients may experience:
- Skin rash
- Depression
- Testicular pain
Rare but serious side effects can include:
- Allergic reactions, including angioedema
- Increased risk of high-grade prostate cancer (as observed in clinical trials)
Drug interaction
- Concomitant use with other 5-alpha-reductase inhibitors (e.g., finasteride) is not recommended due to potential additive effects.
- Dutasteride is primarily metabolized by CYP3A4; caution is advised with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir), which may increase dutasteride exposure.
- No clinically significant interactions have been observed with alpha-blockers (e.g., tamsulosin), often used in combination for BPH management.
- Always inform healthcare providers of all medications, including over-the-counter drugs and supplements.
Missed dose
If a dose is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose. In that case, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed one. Consistent daily dosing is important for optimal efficacy.
Overdose
No specific antidote for dutasteride overdose is known. In case of suspected overdose, symptomatic and supportive measures should be initiated. Dialysis is unlikely to be effective due to high protein binding. If overdose occurs, contact a poison control center or seek emergency medical attention promptly.
Storage
Store at room temperature (20°–25°C or 68°–77°F), with excursions permitted between 15°–30°C (59°–86°F). Keep in the original container to protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider for personalized recommendations and to discuss potential risks and benefits based on individual health status. Do not initiate or discontinue Avodart without medical supervision.
Reviews
“After six months on Avodart, my urinary symptoms have significantly improved. My flow is better, and I no longer wake up multiple times at night. My urologist is pleased with my progress.” – James L., 68
“Although I experienced some initial side effects like reduced libido, they subsided after a few months. The trade-off for improved urinary function has been worth it for me.” – Robert K., 72
“Avodart, combined with an alpha-blocker, has given me the best relief from BPH symptoms I’ve had in years. I appreciate that it’s a once-daily, easy-to-take medication.” – Thomas R., 65
“My PSA levels dropped as expected, which my doctor monitors regularly. It’s reassuring to know I’m reducing my risk of future prostate surgery.” – William D., 70
“I was hesitant due to the potential sexual side effects, but after discussing with my doctor, I started Avodart. The benefits for my BPH have far outweighed the mild side effects I experienced.” – Michael P., 61