Lotrisone: Comprehensive Dual-Action Antifungal and Anti-Inflammatory Relief
Lotrisone
| Product dosage: 10 gr | |||
|---|---|---|---|
| Package (num) | Per tube | Price | Buy |
| 5 | 9.59 $ | 47.97 $ (0%) | 🛒 Add to cart |
| 6 | 8.78 $ | 57.56 $ 52.65 $ (9%) | 🛒 Add to cart |
| 7 | 8.19 $ | 67.16 $ 57.33 $ (15%) | 🛒 Add to cart |
| 8 | 7.75 $ | 76.75 $ 62.01 $ (19%) | 🛒 Add to cart |
| 9 | 7.41 $ | 86.35 $ 66.69 $ (23%) | 🛒 Add to cart |
| 10 | 7.14 $
Best per tube | 95.94 $ 71.37 $ (26%) | 🛒 Add to cart |
| Product dosage: 20 gr | |||
|---|---|---|---|
| Package (num) | Per tube | Price | Buy |
| 2 | 24.57 $ | 49.14 $ (0%) | 🛒 Add to cart |
| 4 | 21.35 $ | 98.28 $ 85.41 $ (13%) | 🛒 Add to cart |
| 8 | 19.45 $ | 196.56 $ 155.61 $ (21%) | 🛒 Add to cart |
| 16 | 18.57 $
Best per tube | 393.12 $ 297.18 $ (24%) | 🛒 Add to cart |
Synonyms | |||
Lotrisone combines clotrimazole, a potent antifungal agent, with betamethasone dipropionate, a high-potency corticosteroid, to deliver targeted treatment for fungal skin infections accompanied by inflammation. This prescription medication is formulated to address both the underlying infection and the associated symptoms such as redness, itching, and swelling, providing patients with effective and rapid symptomatic relief. It is particularly indicated for tinea corporis, tinea cruris, and tinea pedis that present with significant inflammatory components, making it a versatile option in dermatological practice.
Features
- Contains 1% clotrimazole and 0.05% betamethasone dipropionate in a smooth, white cream base
- Available in 15g and 45g tubes for convenient application
- Formulated for topical use only; not for ophthalmic, oral, or intravaginal use
- Combines broad-spectrum antifungal activity with potent anti-inflammatory effects
- Stable emulsion base ensures even distribution and absorption
Benefits
- Rapidly reduces itching, redness, and inflammation associated with fungal infections
- Effectively eradicates common dermatophytes such as Trichophyton rubrum and Trichophyton mentagrophytes
- Dual-action formula addresses both causative organisms and symptomatic discomfort
- Convenient twice-daily application supports patient adherence to treatment regimen
- Minimizes risk of secondary bacterial infections by controlling inflammation and breakdown of skin barrier
- Provides clinically proven efficacy in as little as one week of use for many patients
Common use
Lotrisone is primarily prescribed for the treatment of tinea corporis (ringworm of the body), tinea cruris (jock itch), and tinea pedis (athlete’s foot) where significant inflammation is present. It is also used off-label for certain other dermatophyte infections and inflammatory skin conditions where both antifungal and corticosteroid actions are warranted, though such use should be carefully considered by a healthcare provider based on individual patient factors and clinical presentation.
Dosage and direction
Apply a thin layer of Lotrisone cream to the affected area twice daily, in the morning and evening. Gently massage into the skin until absorbed. Wash hands before and after application unless treating hands. Treatment duration is typically 2-4 weeks, though this may vary based on infection severity and response. Do not use for longer than 4 weeks unless specifically directed by a healthcare provider. Do not cover with occlusive dressings unless advised by a physician, as this may increase systemic absorption of the corticosteroid component.
Precautions
Use only as directed by a healthcare provider. Avoid contact with eyes, mouth, and mucous membranes. Do not apply to open wounds or broken skin. Use with caution in patients with liver impairment. Prolonged use may lead to skin atrophy, striae, telangiectasia, or adrenal suppression. Monitor for signs of secondary infection. Discontinue if irritation develops. Not recommended for use in children under 12 years except under close medical supervision. Use during pregnancy only if clearly needed and potential benefits justify potential risks.
Contraindications
Hypersensitivity to clotrimazole, betamethasone, other imidazoles, or any component of the formulation. Contraindicated in patients with viral skin infections (e.g., herpes simplex, varicella). Should not be used for fungal infections that do not demonstrate significant inflammation. Not indicated for acne rosacea, perioral dermatitis, or other conditions where corticosteroid use may exacerbate the condition.
Possible side effect
Common side effects may include burning, itching, irritation, or dryness at application site. Less frequently, may cause folliculitis, hypertrichosis, hypopigmentation, or allergic contact dermatitis. With prolonged use or excessive application, may cause skin atrophy, striae, miliaria, or secondary infections. Systemic absorption of corticosteroids may potentially lead to adrenal suppression, Cushing’s syndrome, hyperglycemia, or glucosuria, particularly with prolonged use over large areas or with occlusive dressings.
Drug interaction
No specific drug interactions have been formally established with topical Lotrisone. However, systemic absorption of corticosteroids may potentially interact with other medications, particularly in patients with extensive application or impaired skin barrier. Caution should be exercised when using with other topical products that might enhance absorption or cause irritation. Inform your healthcare provider about all medications you are taking, including prescription, over-the-counter, and herbal products.
Missed dose
Apply the missed dose as soon as remembered, unless it is almost time for the next scheduled application. Do not apply double the amount to make up for a missed dose. Resume regular dosing schedule. Consistent application is important for treatment efficacy, but occasional missed doses are unlikely to significantly impact overall outcomes.
Overdose
Topical overdose is unlikely but may occur with excessive application over large body surface areas, particularly with occlusive dressings. Symptoms may include manifestations of systemic corticosteroid excess, such as hypercorticism or adrenal suppression. Treatment involves discontinuation of the medication and appropriate supportive care. In case of accidental ingestion, seek immediate medical attention as systemic effects may occur.
Storage
Store at controlled room temperature between 20°C to 25°C (68°F to 77°F). Do not freeze. Keep tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Keep out of reach of children and pets. Do not use after expiration date printed on packaging. Discard any medication that appears discolored or shows signs of separation.
Disclaimer
This information is provided for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting any new medication or treatment regimen. Individual results may vary. Proper diagnosis by a healthcare provider is essential before using this medication. Do not use this information to self-diagnose or self-treat medical conditions.
Reviews
Clinical studies demonstrate Lotrisone’s efficacy in treating inflammatory fungal infections, with most patients showing significant improvement within the first week of treatment. Dermatologists frequently report high patient satisfaction due to the rapid relief of itching and inflammation. Some practitioners note the importance of appropriate patient selection to avoid corticosteroid-related complications. Patients should follow up with their healthcare provider to ensure complete resolution of the infection and to monitor for potential adverse effects.