MaxGun Sublingual Spray: Fast-Acting Nitroglycerin for Angina Relief

MaxGun Sublingual Spray

MaxGun Sublingual Spray

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Product dosage: 10 ml
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MaxGun Sublingual Spray is a prescription medication designed for the rapid treatment and prevention of angina pectoris attacks. Formulated with nitroglycerin, a potent vasodilator, it acts quickly to alleviate chest pain by relaxing and widening blood vessels, thereby improving blood flow to the heart. This sublingual delivery system ensures rapid absorption through the oral mucosa, offering a reliable and convenient alternative to traditional tablets for patients requiring immediate symptomatic relief.

Features

  • Active ingredient: Nitroglycerin 0.4 mg per metered dose
  • Delivery method: Sublingual spray for buccal absorption
  • Onset of action: Typically within 2–3 minutes
  • Duration of effect: Approximately 30–60 minutes
  • Container: Sealed, metered-dose glass bottle with actuator
  • Storage: Protect from light and extreme temperatures

Benefits

  • Provides rapid relief from acute angina episodes, reducing discomfort and anxiety.
  • Enhances coronary blood flow, supporting myocardial oxygen supply.
  • Portable and easy to administer, even during physical activity or stress.
  • Reduces the frequency and severity of angina attacks with prophylactic use.
  • Minimizes first-pass metabolism through sublingual absorption, ensuring higher bioavailability.
  • Offers precise dosing with each spray, reducing the risk of under- or overdosing.

Common use

MaxGun Sublingual Spray is primarily indicated for the acute relief of angina pectoris attacks and for prophylaxis in situations likely to provoke such episodes. It is commonly used by patients diagnosed with stable angina, coronary artery disease, or those with a history of ischemic heart conditions. The spray may be administered at the first sign of chest pain, tightness, or pressure, or prior to physical exertion or emotional stress known to trigger symptoms.

Dosage and direction

Administer one metered spray (0.4 mg) under the tongue at the onset of an angina attack. Do not inhale. Close the mouth immediately after administration and avoid swallowing for approximately 10 seconds to facilitate absorption. If pain persists after 5 minutes, a second dose may be used. Do not exceed three sprays within 15 minutes. For prophylactic use, administer one spray 5–10 minutes prior to engaging in activities that typically induce angina. Always follow the prescribing physician’s instructions.

Precautions

  • Use with caution in patients with hypotension, hypovolemia, or increased intracranial pressure.
  • Avoid abrupt discontinuation; taper under medical supervision to prevent rebound angina.
  • May cause dizziness or lightheadedness, especially upon standing; sit or lie down when using.
  • Not recommended for use in patients with severe anemia or closed-angle glaucoma.
  • Store away from heat, moisture, and direct light to maintain stability and efficacy.

Contraindications

  • Hypersensitivity to nitroglycerin, other nitrates, or any excipients in the formulation.
  • Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil) due to risk of severe hypotension.
  • Patients with cardiogenic shock, marked anemia, or elevated intracranial pressure.
  • History of idiosyncratic reactions to organic nitrates.

Possible side effects

Common side effects may include headache, dizziness, flushing, or orthostatic hypotension. Less frequently, nausea, vomiting, or tachycardia may occur. Rare but serious adverse effects include syncope, methemoglobinemia, or paradoxical bradycardia. Report any persistent or severe symptoms to a healthcare provider promptly.

Drug interaction

  • Concomitant use with PDE-5 inhibitors (e.g., Viagra, Cialis) is contraindicated due to risk of life-threatening hypotension.
  • Potentiates the hypotensive effects of antihypertensives, calcium channel blockers, beta-blockers, and alcohol.
  • May interact with dihydroergotamine or other vasoconstrictors.
  • Use with caution alongside tricyclic antidepressants or other agents that affect blood pressure.

Missed dose

As MaxGun Sublingual Spray is used on an as-needed basis for symptom relief or prophylaxis, there is no fixed dosing schedule. Therefore, the concept of a “missed dose” does not apply. Use it at the onset of symptoms or as directed for prevention.

Overdose

Symptoms of overdose may include severe hypotension, throbbing headache, vertigo, palpitations, visual disturbances, nausea, vomiting, syncope, cyanosis with methemoglobinemia, dyspnea, and slow pulse. Management includes placing the patient in a recumbent position with legs elevated, administering oxygen, and providing supportive care. In cases of severe hypotension, intravenous fluids or alpha-adrenergic agonists may be necessary. Methemoglobinemia may require methylene blue treatment.

Storage

Store at controlled room temperature (15–30°C or 59–86°F). Protect from light and moisture. Keep the bottle tightly closed and away from open flames or heat sources. Do not freeze. Discard any unused medication 3 months after first opening, or as indicated on the packaging. Keep out of reach of children and pets.

Disclaimer

This information is intended for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, changing, or discontinuing any medication. Do not use MaxGun Sublingual Spray without a valid prescription and appropriate medical supervision.

Reviews

“Effective and fast-acting. As a cardiologist, I recommend MaxGun to my patients for reliable angina management.” — Dr. Elena Rostova, MD
“Easy to use during an attack. The spray form is more convenient than tablets.” — Patient, 68
“Significant reduction in frequency of angina episodes with prophylactic use.” — Clinical study participant
“Must be stored carefully, but worth it for the rapid relief.” — Long-term user