Rocaltrol

Rocaltrol (Calcitriol) is a form of vitamin D, necessary for normal bone development.

Product dosage: 0.25mcg
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30	2.38 $	71.37 $ (0%)	🛒 Add to cart
60	2.03 $	142.74 $ 121.68 $ (15%)	🛒 Add to cart
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270	1.75 $	642.33 $ 473.85 $ (26%)	🛒 Add to cart
360	1.74 $ Best per cap	856.44 $ 625.95 $ (27%)	🛒 Add to cart
Synonyms Calcijex Silkis

Rocaltrol (calcitriol) is a potent, active form of Vitamin D3 prescribed for the management of hypocalcemia in patients undergoing chronic renal dialysis, as well as for the treatment of hypoparathyroidism and metabolic bone disease in patients with chronic kidney disease. It functions by promoting calcium absorption in the intestines and regulating calcium and phosphate levels in the blood, which is critical for bone mineralization and metabolic balance. This medication is a cornerstone therapy for patients with specific endocrine and renal disorders, requiring careful medical supervision for optimal efficacy and safety.

Features

• Contains calcitriol, the biologically active form of Vitamin D3
• Available in oral capsule and liquid formulations for flexible dosing
• Specifically engineered for high bioavailability and rapid onset of action
• Manufactured under strict pharmaceutical standards to ensure purity and consistency
• Requires prescription and regular monitoring of serum calcium, phosphorus, and creatinine levels

Benefits

• Effectively raises low blood calcium levels, reducing the risk of tetany and seizures
• Helps prevent and treat renal osteodystrophy in patients with chronic kidney disease
• Supports normal bone metabolism and mineralization, reducing fracture risk
• Aids in the management of secondary hyperparathyroidism
• Can improve muscle strength and reduce bone pain in affected individuals
• Contributes to overall better management of mineral and bone disorders in renal impairment

Common use

Rocaltrol is primarily indicated for the management of hypocalcemia in patients on chronic renal dialysis. It is also used in the treatment of hypoparathyroidism (post-surgical, idiopathic, or pseudohypoparathyroidism) and for the management of metabolic bone disease in patients with chronic kidney disease not yet on dialysis. Its use is critical in populations where the kidney’s ability to convert Vitamin D to its active form is impaired.

Dosage and direction

Dosage must be individualized based on the patient’s serum calcium levels. The initial dose for most adult patients is 0.25 mcg per day, which may be increased by 0.25 mcg daily at 4–8 week intervals if necessary. For pediatric patients, the dose is based on body weight, typically starting at 0.01–0.015 mcg/kg/day. Regular monitoring of calcium, phosphorus, and creatinine levels is essential. The medication is usually taken orally, once daily, with or without food, but consistency in administration with respect to meals is recommended.

Precautions

Patients should be advised to avoid using non-prescribed calcium supplements or Vitamin D products concurrently. Adherence to a prescribed dietary regimen of calcium intake is crucial. Regular blood tests are necessary to monitor calcium and phosphate levels to avoid hypercalcemia. Use with caution in patients with a history of kidney stones. Patients should maintain adequate hydration unless contraindicated. Alert your physician if you are pregnant, planning to become pregnant, or are breastfeeding.

Contraindications

Rocaltrol is contraindicated in patients with hypercalcemia or Vitamin D toxicity. It should not be used in patients with evidence of hypersensitivity to calcitriol or any of the formulation’s excipients. Use is also contraindicated in patients with abnormally high levels of phosphate in the blood unless hyperphosphatemia is appropriately managed.

Possible side effect

Common side effects may include headache, nausea, vomiting, constipation, dry mouth, muscle pain, and metallic taste. More serious side effects can include early signs of hypercalcemia such as weakness, fatigue, drowsiness, and increased thirst or urination. Rare but severe reactions may involve allergic responses, pancreatitis, or soft tissue calcification. Any unusual symptoms should be reported to a healthcare provider immediately.

Drug interaction

Rocaltrol may interact with thiazide diuretics (increasing risk of hypercalcemia), cholestyramine or mineral oil (reducing absorption), corticosteroids (counteracting effects), and phosphate-binding agents or magnesium-containing antacids (risk of hypermagnesemia). Concurrent use with digoxin may increase the risk of cardiac arrhythmias. Always inform your healthcare provider of all medications, including over-the-counter drugs and supplements.

Missed dose

If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next dose. In that case, skip the missed dose and resume the regular schedule. Do not double the dose to catch up. Consistent daily administration is important for maintaining stable calcium levels.

Overdose

Overdose of Rocaltrol may lead to hypercalcemia, hypercalciuria, and hyperphosphatemia. Symptoms include anorexia, nausea, vomiting, constipation, weakness, confusion, and in severe cases, cardiac arrhythmias or renal impairment. Treatment involves immediate discontinuation of the drug, a low-calcium diet, adequate hydration, and in severe cases, hospitalization for more intensive management such as loop diuretics or corticosteroids under close monitoring.

Storage

Store at room temperature (20–25°C or 68–77°F), away from light, moisture, and heat. Keep the container tightly closed. Do not freeze the liquid formulation. Keep out of reach of children and pets. Do not use beyond the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult your physician or qualified healthcare provider for any questions regarding a medical condition or before starting any new treatment. Do not disregard professional medical advice or delay seeking it because of something you have read here.

Reviews

“After starting Rocaltrol for my CKD-related hypocalcemia, my energy levels improved significantly and my latest bone density scan showed marked improvement. Requires strict adherence to monitoring, but well worth it.” – Maria L., 58

“As an endocrinologist, I find Rocaltrol indispensable for managing post-thyroidectomy hypoparathyroidism. It offers predictable control over calcium levels when dosed and monitored correctly.” – Dr. A. Reynolds, MD

“Initially experienced some nausea, but it subsided after the first week. My calcium levels have stabilized, and I haven’t had a hypocalcemic episode in over six months.” – James K., 42