Tenovate: Advanced Topical Corticosteroid for Rapid Inflammation Control
Tenovate
| Product dosage: 15g | |||
|---|---|---|---|
| Package (num) | Per tube | Price | Buy |
| 4 | 12.29 $ | 49.14 $ (0%) | 🛒 Add to cart |
| 5 | 11.70 $ | 61.42 $ 58.50 $ (5%) | 🛒 Add to cart |
| 6 | 11.51 $ | 73.71 $ 69.03 $ (6%) | 🛒 Add to cart |
| 7 | 11.03 $ | 86.00 $ 77.22 $ (10%) | 🛒 Add to cart |
| 8 | 10.53 $ | 98.28 $ 84.24 $ (14%) | 🛒 Add to cart |
| 9 | 9.88 $ | 110.56 $ 88.92 $ (20%) | 🛒 Add to cart |
| 10 | 9.59 $
Best per tube | 122.85 $ 95.94 $ (22%) | 🛒 Add to cart |
Tenovate is a high-potency topical corticosteroid formulation containing Clobetasol Propionate 0.05%, designed for the targeted treatment of severe inflammatory skin conditions. It offers rapid anti-inflammatory, antipruritic, and vasoconstrictive actions, making it a cornerstone in dermatological therapy for conditions unresponsive to lower-potency corticosteroids. This product is indicated for short-term use under medical supervision to achieve swift symptom control while minimizing systemic exposure. Its optimized vehicle system ensures enhanced cutaneous penetration and localized therapeutic effect.
Features
- Contains Clobetasol Propionate 0.05% as the active pharmaceutical ingredient
- Available in cream, ointment, and scalp application formulations
- Enhanced lipophilic base for superior skin barrier penetration
- Fluorinated corticosteroid with high receptor affinity
- Minimal systemic absorption when used as directed
- Paraben-free and hypoallergenic formulation options
- Stable chemical composition with 24-month shelf life
- Precision dosing capability across different formulations
Benefits
- Provides rapid relief from inflammation, itching, and erythema within 24-48 hours
- Reduces plaque thickness and scaling in psoriatic lesions effectively
- Minimizes recurrence through proper short-term treatment courses
- Targeted action limits systemic side effects when used appropriately
- Improves quality of life through swift symptom resolution
- Compatible with various dermatological combination therapies
Common use
Tenovate is primarily prescribed for short-term treatment of severe corticosteroid-responsive dermatoses including psoriasis (especially plaque-type), refractory eczema, lichen planus, discoid lupus erythematosus, and other immune-mediated skin conditions. It is particularly effective in managing thickened, hyperkeratotic lesions on elbows, knees, and palms/soles. Dermatologists may also prescribe it for severe contact dermatitis cases where conventional steroids have proven inadequate. The medication is typically reserved for areas resistant to lower-potency steroids and for acute flare management.
Dosage and direction
Apply a thin film to affected areas once or twice daily, depending on severity and physician recommendation. For most conditions, application frequency should not exceed twice daily. The total weekly dosage should not exceed 50 grams. Treatment duration is generally limited to 2-4 weeks, with occlusive dressings used only under strict medical supervision. For scalp applications, apply sparingly to dry scalp and massage gently until absorbed. Wash hands thoroughly after application unless treating hands. Discontinue use once control is achieved; do not use continuously beyond 4 weeks without medical reassessment.
Precautions
Use under strict medical supervision; not for ophthalmic, oral, or intravaginal use. Avoid application to face, groin, or axillae due to higher absorption rates. Monitor for signs of skin atrophy, telangiectasia, or hypopigmentation with prolonged use. Caution advised in pediatric and geriatric patients due to increased percutaneous absorption. Do not use on large surface areas, broken skin, or infected lesions without concurrent antimicrobial therapy. Periodic evaluation of HPA axis function recommended with extended use. Pregnancy Category C: use only if potential benefit justifies potential risk.
Contraindications
Hypersensitivity to clobetasol propionate or any formulation components. Contraindicated in rosacea, perioral dermatitis, acne vulgaris, and cutaneous infections (viral, fungal, or bacterial without appropriate antimicrobial coverage). Not recommended for patients with untreated systemic infections, immunocompromised states, or circulating vaccinia virus. Absolute contraindication in patients with history of hypersensitivity reactions to corticosteroids. Avoid use in patients with skin conditions where enhanced systemic absorption might occur (e.g., erythroderma, extensive psoriasis).
Possible side effect
Local reactions: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation. With prolonged use: skin atrophy, striae, telangiectasia, miliaria, secondary infection. Systemic absorption may cause HPA axis suppression, glucosuria, hypertension, Cushing’s syndrome (with excessive use). Rare reports: contact dermatitis, paradoxical worsening, allergic reactions. Discontinue and consult physician if severe irritation or signs of systemic absorption develop. Most local adverse effects are reversible upon discontinuation.
Drug interaction
No specific drug interaction studies conducted; however, systemic absorption may potentiate effects of other corticosteroids. Concurrent use with other topical products may enhance absorption or cause interactions. Caution with other immunosuppressive agents due to additive effects. Avoid concomitant use with other topical corticosteroids. May interact with drugs affecting liver enzyme systems (CYP3A4 inducers/inhibitors) if significant systemic absorption occurs.
Missed dose
Apply as soon as remembered if within a few hours of scheduled time. If close to next dose time, skip missed dose and resume regular schedule. Do not double application to compensate. Maintain consistent application intervals for optimal therapeutic effect. Irregular application may reduce efficacy and prolong treatment duration.
Overdose
Topical overdose may cause systemic effects including Cushing’s syndrome, hyperglycemia, glucosuria, HPA axis suppression. Acute overdose requires discontinuation and symptomatic management. Chronic overdose manifests as steroid withdrawal symptoms upon discontinuation. In case of accidental ingestion, seek immediate medical attention. Topical decontamination usually unnecessary; supportive care based on symptoms.
Storage
Store at controlled room temperature (15-30°C). Keep tube tightly closed when not in use. Protect from light and excessive heat. Do not freeze. Keep out of reach of children. Discard any product showing signs of deterioration or beyond expiration date. Do not store in bathroom due to humidity variations.
Disclaimer
This information is for educational purposes only and does not replace professional medical advice. Use strictly as prescribed by qualified healthcare provider. Individual results may vary based on condition severity, application technique, and patient factors. Full prescribing information available from manufacturer upon request.
Reviews
“Dermatologists consistently report excellent efficacy in refractory psoriasis cases, with noticeable improvement within 72 hours. Clinical studies demonstrate 85% improvement in PASI scores after 4 weeks of appropriate use. Patients describe significant relief from itching and scaling. Medical literature supports its position as gold-standard high-potency topical steroid. Long-term safety profile well-established when used according to guidelines.”