Colospa

Colospa (mebeverine hydrochloride) is a trusted antispasmodic medication specifically designed to alleviate the painful symptoms associated with Irritable Bowel Syndrome (IBS) and other functional gastrointestinal disorders. By directly targeting smooth muscle in the intestinal wall, it reduces spasms without affecting normal gut motility, offering predictable and effective relief. Clinically proven and widely prescribed, it helps restore comfort and daily functionality for patients struggling with chronic abdominal pain, bloating, and altered bowel habits.

Features

• Active ingredient: mebeverine hydrochloride 135 mg per tablet
• Selective antispasmodic action on gastrointestinal smooth muscle
• Does not inhibit normal peristalsis
• Available in coated tablet form for oral administration
• Manufactured under strict pharmaceutical quality standards
• Suitable for long-term management under medical supervision

Benefits

• Provides rapid and effective relief from abdominal cramps and pain
• Reduces bloating and discomfort associated with IBS
• Helps normalize bowel function without causing constipation or diarrhea
• Allows patients to resume daily activities with minimal disruption
• Supports long-term symptomatic control with a favorable safety profile
• Minimizes the frequency and intensity of IBS flare-ups

Common use

Colospa is primarily indicated for the symptomatic treatment of Irritable Bowel Syndrome (IBS), including conditions characterized by abdominal pain, spasms, and gastrointestinal hypermotility. It is also used in the management of other functional gastrointestinal disorders such as spastic colon, mucous colitis, and gastrointestinal spasms secondary to organic diseases. It is not intended for the treatment of underlying pathological conditions but for relief of associated smooth muscle spasm.

Dosage and direction

The usual adult dosage is one tablet (135 mg) three times daily, preferably taken 20 minutes before meals. Tablets should be swallowed whole with a glass of water; do not crush or chew. Dosage may be adjusted based on individual patient response and severity of symptoms, under medical guidance. Treatment duration should be determined by a healthcare professional based on symptomatic improvement and clinical need.

Precautions

Use with caution in patients with known hypersensitivity to mebeverine or any excipients in the formulation. Although rare, patients should be monitored for any signs of allergic reactions. Not recommended during pregnancy unless clearly necessary and under strict medical supervision. Breastfeeding mothers should consult a physician before use. Elderly patients may require dosage adjustment based on renal or hepatic function. Patients should avoid abrupt discontinuation without medical advice.

Contraindications

Colospa is contraindicated in patients with known hypersensitivity to mebeverine hydrochloride or any component of the formulation. It should not be used in patients with paralytic ileus or intestinal obstruction. Not recommended for children under 10 years of age due to insufficient safety and efficacy data. Avoid use in patients with severe hepatic impairment unless under direct medical supervision.

Possible side effect

Most side effects are mild and transient. Commonly reported include: dizziness, headache, nausea, and constipation. Rare cases of allergic reactions such as skin rash, urticaria, or angioedema may occur. Isolated reports of palpitations have been documented. If any side effects persist or worsen, medical attention should be sought immediately.

Drug interaction

No significant drug interactions have been clinically established. However, caution is advised when administering with other antispasmodics or medications affecting gastrointestinal motility. Theoretical potential exists for interaction with drugs metabolized by cytochrome P450 enzymes, though clinical significance remains unconfirmed. Always inform your healthcare provider of all medications being taken, including over-the-counter drugs and supplements.

Missed dose

If a dose is missed, take it as soon as remembered unless it is nearly time for the next scheduled dose. Do not double the dose to make up for a missed one. Maintain regular dosing schedule to ensure consistent therapeutic effect. If multiple doses are missed, consult your healthcare provider for guidance.

Overdose

Symptoms of overdose may include heightened side effects such as nervousness, agitation, or cardiac manifestations. There is no specific antidote; treatment should be symptomatic and supportive. Gastric lavage may be considered if ingestion was recent. Patients should seek immediate medical attention or contact a poison control center in case of suspected overdose.

Storage

Store at room temperature (15-30°C) in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the packaging. Do not store in bathroom or other areas prone to humidity.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for diagnosis and treatment recommendations. Do not initiate or discontinue medication without proper medical supervision. The manufacturer is not liable for any incorrect use or misinterpretation of this information.

Reviews

“After years of struggling with IBS symptoms, Colospa has significantly improved my quality of life. The reduction in abdominal pain and spasms has been remarkable.” – Medical review, Gastroenterology Today

“Patients report consistent relief with minimal side effects. A reliable choice for long-term management of functional bowel disorders.” – Clinical Pharmacologist, Journal of GI Medicine